Ephedra and Ephedrine

Ephedra/ephedrine: cardiovascular and CNS effects.

The Ephedrine Assay of Chinese Ephedra.*

As set forth in a recent note we have shown that Chinese Ma Huang is obtained from various species of Ephedra, E. eguisetina, Bunge; E. sinica, Stapf ; and E. mahuang, Liu. So far there has been no differentiation made between the various samples of this drug which occur upon the Chinese market. However, irrespective of the possible variation in the drug samples we consider i t is essential tha...

Efficacy and safety of ephedra and ephedrine for weight loss and athletic performance: a meta-analysis.

CONTEXT Ephedra and ephedrine sometimes are used for weight loss or enhanced athletic performance, but the efficacy and safety of these compounds are uncertain. OBJECTIVE To assess the efficacy and safety of ephedra and ephedrine used for weight loss and enhanced athletic performance. DATA SOURCES We searched 9 databases using the terms ephedra, ephedrine, adverse effect, side effect, effic...

Ephedra and ephedrine for weight loss and athletic performance enhancement: clinical efficacy and side effects.

This report may be used, in whole or in part, as the basis for development of clinical practice guidelines and other quality enhancement tools, or a basis for reimbursement and coverage policies. AHRQ or U.S. Department of Health and Human Services endorsement of such derivative products may not be stated or implied. AHRQ is the lead Federal agency charged with supporting research designed to i...

Separation and determination of ephedrine alkaloids and tetramethylpyrazine in Ephedra sinica Stapf by gas chromatography-mass spectrometry.

A simple, sensitive, and reliable method using gas chromatography (GC)-mass spectrometry (MS) is developed for the simultaneous determination of ephedrine alkaloids and 2,3,5,6-tetramethylpyrazine (TMP) in Ephedra sinica Stapf. The sample is extracted with ethyl ether and submitted to GC-MS for identification and quantitation without derivatization. The column used for GC is an HP-5 (30.0 m x 2...